Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.74 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.74 |
| ▸ | MMP2 | P08253 | 6/20 | 0.67 |
| ▸ | MMP3 | P08254 | 5/20 | 0.67 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521624 | 0.99 | HDAC1 (0.71) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7520274 | 0.88 | MMP2 (0.80) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL5097470 | 0.88 | MMP2 (0.80) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL6252232 | 0.88 | MMP2 (0.80) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL13862226 | 0.88 | MMP2 (0.80) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9128810 | 0.88 | MMP2 (0.80) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8657014 | 0.88 | MMP2 (0.80) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4273348 | 0.87 | MMP2 (0.82) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL1274377 | 0.86 | HDAC1 (0.66) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4408915 | 0.86 | HDAC1 (0.66) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |