SCHEMBL7399348

SCHEMBL7399348

Nc1ccccc1-c1nc(-c2ccccc2)no1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 1/20 0.71
SMN1; SMN2 Q16637 6/20 0.65
MAPT P10636 5/20 0.65
NFKB1 P19838 4/20 0.65
NFKB2 Q00653 4/20 0.65
RELA Q04206 4/20 0.65
RAB9A P51151 4/20 0.65
MAPK1 P28482 3/20 0.65
L3MBTL1 Q9Y468 3/20 0.65
TP53 P04637 3/20 0.65
NPC1 O15118 3/20 0.65
MEN1 O00255 1/20 0.65
PKM P14618 1/20 0.65
KMT2A Q03164 1/20 0.65
CHUK O15111 1/20 0.65
CASP3 P42574 1/20 0.65
TXNRD1 Q16881 1/20 0.65
SENP8 Q96LD8 1/20 0.65
SENP7 Q9BQF6 1/20 0.65
SENP6 Q9GZR1 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2972736 0.87 NPC1 (0.60) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL11487507 0.86 BCHE (0.81) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL11476974 0.83 SMN1; SMN2 (0.62) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL9741006 0.81 NR1H4 (0.62) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL28642673 0.79 RAB9A (1.00) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL5736756 0.79 CASP3 (1.00) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL28653242 0.79 SMN1; SMN2 (1.00) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL1473020 0.78 NR1H4 (1.00) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL28240691 0.78 GPR55 (0.65) GPR55SMN1; SMN2MAPTNFKB1NFKB2
SCHEMBL4186253 0.77 SMN1; SMN2 (0.68) SMN1; SMN2MAPTRAB9AMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8382857-B2 Method for the reactive coloration of leather BASF SE (DE) 2013-02-26 US disclosed
US-8382857-B2 Method for the reactive coloration of leather BASF SE (DE) 2013-02-26 US disclosed
US-8372161-B2 Method for the reactive coloring of leather BASF SE (DE) 2013-02-12 US disclosed
US-8372161-B2 Method for the reactive coloring of leather BASF SE (DE) 2013-02-12 US disclosed
EP-1756355-B1 METHOD FOR THE REACTIVE COLORATION OF LEATHER BASF SE (DE) 2010-08-25 EP disclosed
US-20070234488-A1 Method for the Reactive Coloration of Leather BASF AKTIENGESELLSCHAFT (DE) 2007-10-11 US disclosed
US-20070234488-A1 Method for the Reactive Coloration of Leather BASF AKTIENGESELLSCHAFT (DE) 2007-10-11 US disclosed
US-20070033746-A1 Method for the reactive coloring of leather BASF AKTIENGESSELLSCHAFT (DE) 2007-02-15 US disclosed
US-20070033746-A1 Method for the reactive coloring of leather BASF AKTIENGESSELLSCHAFT (DE) 2007-02-15 US disclosed
EP-0716743-B1 METHOD OF DETECTING NAPHTHYLAMINES IN MINERAL OILS BASF AG (DE) 2000-06-14 EP disclosed
EP-0384310-B1 Process for the preparation of phenyl oxadiazolyl anilines BASF AG (DE) 1994-07-06 EP disclosed
EP-0419397-B1 Substituted urea compounds and their preparation and use NOVO NORDISK AS (DK) 1994-06-08 EP disclosed
EP-0491770-A1 SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1992-07-01 EP disclosed
US-5104991-A PREPARATION OF PHENYLOXADIAZOLYLANILINES BASF AKTIENGESELLSCHAFT (DE) 1992-04-14 US disclosed
EP-0419397-A1 Substituted urea compounds and their preparation and use NOVO NORDISK A/S (DK) 1991-03-27 EP disclosed
WO-1991003475-A1 SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1991-03-21 WO disclosed
EP-0385330-A2 Mixtures of dyestuffs comprising azo compounds on the basis of phenylox diazolyl aniline BASF Aktiengesellschaft (DE) 1990-09-05 EP disclosed
EP-0384310-A2 Process for the preparation of phenyl oxadiazolyl anilines BASF Aktiengesellschaft (DE) 1990-08-29 EP disclosed
US-4368582-A Process for drying finely divided pigments BASF AKTIENGESELLSCHAFT (DE) 1983-01-18 US disclosed
US-4229343-A Azo dyes from an oxadiazolyl-substituted aniline BASF AKTIENGESELLSCHAFT (DE) 1980-10-21 US disclosed