Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399380 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BHRH3KDM4EALDH1A1 | |
| SCHEMBL7788302 | 0.83 | ITGB3 (0.67) | ITGB3ITGA2BHRH3 | |
| SCHEMBL7788361 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7298004 | 0.81 | ITGB3 (0.67) | ITGB3ITGA2BHRH3MEN1KMT2A | |
| SCHEMBL7788333 | 0.81 | DRD2 (0.51) | ITGB3ITGA2BHRH3 | |
| SCHEMBL7297997 | 0.81 | ITGB3 (0.67) | ITGB3ITGA2BHRH3MEN1KMT2A | |
| SCHEMBL7787513 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7298008 | 0.81 | ITGB3 (0.67) | ITGB3ITGA2BHRH3MEN1KMT2A | |
| SCHEMBL8303817 | 0.80 | KDM4E (0.40) | ITGB3ITGA2BHRH3KDM4EALDH1A1 | |
| SCHEMBL7790715 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |