Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300631 | 0.82 | GRIN2B (0.40) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8300676 | 0.82 | KDM4E (0.42) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8301361 | 0.81 | CYP2D6 (0.39) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8299936 | 0.81 | KDM4E (0.41) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8301126 | 0.80 | KDM4E (0.40) | KDM4EMEN1ALDH1A1KMT2ATRPV6 | |
| SCHEMBL8615320 | 0.80 | KDM2B (0.34) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL7399382 | 0.80 | ITGB3 (0.49) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL7399380 | 0.80 | ITGB3 (0.49) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8301327 | 0.80 | KDM4E (0.43) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8619232 | 0.78 | KDM4E (0.35) | KDM4EMEN1ALDH1A1KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| EP-0808306-A1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024586-A1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-08-15 | — | — | WO | disclosed |