Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 20/20 | 1.00 |
| ▸ | MMP2 | P08253 | 5/20 | 1.00 |
| ▸ | MMP1 | P03956 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413845 | 0.89 | MMP3 (0.80) | MMP3MMP2MMP1 | |
| SCHEMBL7398636 | 0.80 | MMP3 (0.79) | MMP3MMP2MMP1 | |
| SCHEMBL7606130 | 0.80 | MMP3 (0.82) | MMP3MMP2MMP1 | |
| SCHEMBL7606124 | 0.80 | MMP3 (0.82) | MMP3MMP2MMP1 | |
| SCHEMBL7396919 | 0.80 | MMP3 (1.00) | MMP3MMP2MMP1 | |
| SCHEMBL9069179 | 0.78 | MME (0.73) | MMP3MMP2 | |
| SCHEMBL23616375 | 0.77 | MMP3 (0.66) | MMP3MMP2MMP1 | |
| SCHEMBL7400918 | 0.76 | MMP3 (1.00) | MMP3MMP2 | |
| SCHEMBL7404150 | 0.76 | MMP3 (0.81) | MMP3MMP2MMP1 | |
| SCHEMBL6414131 | 0.75 | MME (0.77) | MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679700-A | STROMELYSIN INHIBITOR | MERCK & CO., INC. (US) | 1997-10-21 | — | — | US | claimed |
| WO-1993014112-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-07-22 | — | — | WO | claimed |
| US-5679700-A | STROMELYSIN INHIBITOR | MERCK & CO., INC. (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0623143-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO. INC. (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014112-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-07-22 | — | — | WO | disclosed |