Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 20/20 | 0.82 |
| ▸ | MMP1 | P03956 | 2/20 | 0.82 |
| ▸ | MMP2 | P08253 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606130 | 1.00 | MMP3 (0.82) | MMP3MMP1MMP2 | |
| SCHEMBL7497156 | 0.82 | MMP3 (0.55) | MMP3MMP1MMP2 | |
| SCHEMBL7497160 | 0.82 | MMP3 (0.55) | MMP3MMP1MMP2 | |
| SCHEMBL7399502 | 0.80 | MMP3 (1.00) | MMP3MMP1MMP2 | |
| SCHEMBL9698601 | 0.80 | HSD17B10 (0.56) | MMP3MMP1 | |
| SCHEMBL18791049 | 0.79 | CTSK (0.75) | MMP3MMP1 | |
| SCHEMBL28367764 | 0.79 | CTSK (0.75) | MMP3MMP1 | |
| SCHEMBL7398636 | 0.77 | MMP3 (0.79) | MMP3MMP1MMP2 | |
| SCHEMBL9697717 | 0.75 | KYNU (0.55) | MMP3MMP1 | |
| SCHEMBL9697750 | 0.74 | MMP3 (0.46) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623143-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO. INC. (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014112-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-07-22 | — | — | WO | disclosed |