Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 18/20 | 0.66 |
| ▸ | MMP2 | P08253 | 7/20 | 0.62 |
| ▸ | MMP1 | P03956 | 3/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616285 | 0.86 | MME (0.55) | MMP3MMP2 | |
| SCHEMBL9446563 | 0.85 | FPR1 (0.63) | MMP3MMP2MMP1CAPN1 | |
| SCHEMBL9446555 | 0.85 | FPR1 (0.63) | MMP3MMP2MMP1CAPN1 | |
| SCHEMBL23616270 | 0.84 | SMN1; SMN2 (0.50) | MMP2MMP1 | |
| SCHEMBL23616293 | 0.82 | CAPN1 (0.56) | MMP2MMP1CAPN1 | |
| SCHEMBL23616297 | 0.82 | CTSL (0.55) | MMP3CAPN1 | |
| SCHEMBL23616279 | 0.82 | CTSL (0.55) | MMP3CAPN1 | |
| SCHEMBL23616223 | 0.79 | PSMB5 (0.54) | — | |
| SCHEMBL10272569 | 0.79 | MMP1 (0.62) | MMP3MMP2MMP1 | |
| SCHEMBL23616378 | 0.78 | PSMB5 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297678-B1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LTD (IN) | 2021-07-07 | — | — | EP | disclosed |