Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399114 | 0.88 | KMT2A (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6L3MBTL1 | |
| SCHEMBL12469312 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6RAB9A | |
| SCHEMBL8437522 | 0.77 | SLC6A2 (0.38) | LMNASLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL4051628 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM3 | |
| SCHEMBL5214565 | 0.76 | SLC6A2 (0.37) | LMNASLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL22261624 | 0.74 | LMNA (0.44) | LMNARAB9AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL4439262 | 0.74 | EPHX2 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1MEN1 | |
| SCHEMBL17560116 | 0.74 | TACR1 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6CHRM3 | |
| SCHEMBL4442462 | 0.73 | MEN1 (0.36) | LMNASLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7399910 | 0.73 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714299-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0714299-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995002405-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-01-26 | — | — | WO | disclosed |