Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400559 | 0.94 | L3MBTL1 (0.47) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL7403129 | 0.93 | GNAI3 (0.49) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL7455560 | 0.81 | HRH3 (0.57) | GNAO1ACHEHRH3CYP1A2MAPK1 | |
| SCHEMBL4666488 | 0.80 | HRH3 (0.58) | GNAO1ACHEHRH3MEN1KMT2A | |
| SCHEMBL7407892 | 0.79 | GNAI3 (0.51) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL7447647 | 0.78 | SIGMAR1 (0.56) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL7399289 | 0.78 | SIGMAR1 (0.56) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL7401263 | 0.78 | SIGMAR1 (0.56) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL4664118 | 0.78 | HRH3 (0.56) | GNAO1ACHEHRH3MEN1KMT2A | |
| SCHEMBL22223257 | 0.78 | GNAI3 (0.74) | GNAI3GNAO1GNAI1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024390-A1 | NOVEL PHENYL(-ALKYL/ALKOXY)-1-AMINOALKYL-SUBSTITUTED PIPERIDINES AND PYRROLIDINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-09-14 | — | — | WO | disclosed |