Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399836 | 1.00 | ENPEP (0.36) | ENPEPCYP1A2ACEFOLH1 | |
| Amantadine SCHEMBL9298960 | 0.82 | THRB (0.38) | — | |
| Amantadine SCHEMBL7435558 | 0.82 | THRB (0.38) | — | |
| SCHEMBL3218131 | 0.80 | ENPEP (0.35) | ENPEPCYP1A2ACE | |
| SCHEMBL3218126 | 0.80 | ENPEP (0.35) | ENPEPCYP1A2ACE | |
| SCHEMBL6472491 | 0.80 | ENPEP (0.35) | ENPEPCYP1A2ACE | |
| SCHEMBL7397291 | 0.79 | ENPEP (0.34) | ENPEPCYP1A2ACE | |
| SCHEMBL7397575 | 0.79 | ENPEP (0.34) | ENPEPCYP1A2ACE | |
| SCHEMBL7398558 | 0.79 | ENPEP (0.34) | ENPEPCYP1A2 | |
| SCHEMBL7397297 | 0.79 | ENPEP (0.34) | ENPEPCYP1A2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | claimed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | claimed |
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | disclosed |