Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398554 | 1.00 | ENPEP (0.34) | ENPEPCYP1A2 | |
| Amantadine SCHEMBL7398970 | 0.83 | THRB (0.36) | — | |
| Amantadine SCHEMBL7397271 | 0.83 | THRB (0.36) | — | |
| Amantadine SCHEMBL7397276 | 0.83 | THRB (0.36) | — | |
| SCHEMBL7396705 | 0.81 | ENPEP (0.33) | ENPEP | |
| SCHEMBL7396708 | 0.81 | ENPEP (0.33) | ENPEP | |
| SCHEMBL7395742 | 0.80 | MAPK1 (0.37) | ENPEP | |
| SCHEMBL7395739 | 0.80 | MAPK1 (0.37) | ENPEP | |
| SCHEMBL9240824 | 0.79 | PRKCA (0.42) | ENPEP | |
| SCHEMBL9240818 | 0.79 | PRKCA (0.42) | ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | claimed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | claimed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | claimed |
| US-5478946-A | Treating vascular system disorders or cartilage diseases | ABBOTT LABORATORIES (US) | 1995-12-26 | — | — | US | disclosed |