Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365545 | 0.76 | TBXAS1 (0.49) | LMNASMN1; SMN2EPHX2TBXAS1KEAP1 | |
| SCHEMBL7365547 | 0.76 | TBXAS1 (0.49) | LMNASMN1; SMN2EPHX2TBXAS1KEAP1 | |
| SCHEMBL9323799 | 0.73 | NAPRT (0.54) | LMNASMN1; SMN2HTTEPHX2KEAP1 | |
| SCHEMBL9323795 | 0.73 | NAPRT (0.54) | LMNASMN1; SMN2HTTEPHX2KEAP1 | |
| SCHEMBL7399982 | 0.70 | TBXAS1 (0.49) | LMNASMN1; SMN2EPHX2TBXAS1CYP2C9 | |
| SCHEMBL23655466 | 0.68 | CHRNA7 (0.57) | TBXAS1L3MBTL1 | |
| SCHEMBL10666387 | 0.68 | KMT2A (0.51) | LMNASMN1; SMN2HTTEPHX2KEAP1 | |
| SCHEMBL368449 | 0.66 | GPBAR1 (0.76) | LMNAGPBAR1SMN1; SMN2HPGDHTT | |
| SCHEMBL363952 | 0.66 | GPBAR1 (0.76) | LMNAGPBAR1SMN1; SMN2HPGDHTT | |
| SCHEMBL368448 | 0.66 | GPBAR1 (0.76) | LMNAGPBAR1SMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993019047-A1 | TETRAHIDROPYRIDINYL (3/4) SUBSTITUED OXIMES HAVING SIGMA RECEPTOR AFFINITY AND THEIR USE IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM CONDITIONS | WARNER-LAMBERT COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |