Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116004 | 0.80 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28561602 | 0.79 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7394357 | 0.79 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29145079 | 0.78 | L3MBTL1 (0.64) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL843331 | 0.77 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6890976 | 0.76 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8362182 | 0.75 | L3MBTL1 (0.68) | SMN1; SMN2KMT2AMEN1ALDH1A1PKM | |
| SCHEMBL25168045 | 0.74 | L3MBTL1 (0.46) | KMT2AMEN1KDM4EALDH1A1PKM | |
| SCHEMBL9267030 | 0.73 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16341726 | 0.72 | MEN1 (0.45) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042224-A1 | CARBOXYAMIDO DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2001-06-14 | — | — | WO | disclosed |