Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445164 | 0.75 | GRM5 (0.40) | GRM5HTTLMNATDP1P2RX7 | |
| SCHEMBL8508286 | 0.74 | GRM5 (0.51) | IDO1GRM5HTTALOX15GLO1 | |
| SCHEMBL16162445 | 0.73 | IDO1 (0.56) | IDO1GRM5HTTLMNAPOLB | |
| SCHEMBL4726651 | 0.72 | TTR (0.42) | IDO1HTTLMNATDP1POLB | |
| Hydrochloric Acid SCHEMBL28205807 | 0.71 | COMT (0.50) | HTTALOX15LMNATDP1POLB | |
| SCHEMBL7961505 | 0.71 | L3MBTL1 (0.43) | LMNAPOLBKDM4EALDH1A1MAPT | |
| SCHEMBL4998230 | 0.71 | KDM4E (0.45) | HTTALOX15LMNATDP1P2RX7 | |
| SCHEMBL27879838 | 0.70 | ALDH1A1 (0.50) | IDO1GRM5HTTPOLBBRD4 | |
| SCHEMBL28051960 | 0.70 | MKNK1 (0.50) | IDO1GRM5HTTBRD4P2RX7 | |
| SCHEMBL8415045 | 0.69 | GRM5 (0.50) | IDO1GRM5HTTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |