SCHEMBL7445164

SCHEMBL7445164

CCCc1cccnc1S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.40
LMNA P02545 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 3/20 0.36
COMT P21964 2/20 0.36
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.34
CYP1A2 P05177 1/20 0.34
ALOX12 P18054 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
TSHR P16473 1/20 0.34
P2RX7 Q99572 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL28982029 0.91 GRM5 (0.35) GRM5LMNATDP1KMT2AKDM4E
Sulfuric Acid SCHEMBL28693835 0.89 TSHR (0.37) LMNATDP1KMT2AKDM4ECOMT
SCHEMBL27807031 0.87 LIPG (0.45) TDP1L3MBTL1
SCHEMBL27807092 0.87 LIPG (0.45) TDP1L3MBTL1
SCHEMBL3717899 0.80 COMT (0.41) LMNATDP1KMT2AKDM4ECOMT
SCHEMBL27866602 0.75 KDM4E (0.41) LMNATDP1KMT2AKDM4ECOMT
SCHEMBL7400141 0.75 IDO1 (0.45) GRM5LMNATDP1KDM4ECOMT
SCHEMBL28189822 0.75 LIMK2 (0.46) LMNATDP1KDM4EMAPTHTT
SCHEMBL7075262 0.74 GRM5 (0.50) GRM5KDM4EMAPTL3MBTL1CYP1A2
SCHEMBL28202900 0.73 CA2 (0.44) KMT2ACOMTSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023070961-A1 ACID/PHOTOCATALYTIC OXIDATION REACTION OF BENZYLIC CARBON-HYDROGEN BOND IN AROMATIC COMPOUND 南京工业大学 2023-05-04 WO disclosed
EP-0799209-A1 NOVEL SULFONAMIDES F. HOFFMANN-LA ROCHE AG (CH) 1997-10-08 EP disclosed
EP-0799206-A1 ARYL- AND HETARYL-SULFONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 1997-10-08 EP disclosed
WO-1996019455-A1 ARYL- AND HETARYL-SULFONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 1996-06-27 WO disclosed
WO-1996019459-A1 NOVEL SULFONAMIDES F. HOFFMANN-LA ROCHE AG (CH) 1996-06-27 WO disclosed