Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 5/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547343 | 1.00 | CHEK1 (0.37) | CHEK1MAP2K1MAPTLMNABCHE | |
| SCHEMBL7400404 | 1.00 | CHEK1 (0.37) | CHEK1MAP2K1MAPTLMNABCHE | |
| SCHEMBL7444417 | 0.94 | EHMT2 (0.35) | CHEK1LMNABCHEACHENSD2 | |
| SCHEMBL7393752 | 0.94 | EHMT2 (0.35) | CHEK1LMNABCHEACHENSD2 | |
| SCHEMBL7393757 | 0.94 | EHMT2 (0.35) | CHEK1LMNABCHEACHENSD2 | |
| SCHEMBL7403386 | 0.93 | EHMT2 (0.36) | CHEK1LMNABCHEACHEALDH1A1 | |
| SCHEMBL7403389 | 0.93 | EHMT2 (0.36) | CHEK1LMNABCHEACHEALDH1A1 | |
| SCHEMBL7445293 | 0.93 | EHMT2 (0.36) | CHEK1LMNABCHEACHEALDH1A1 | |
| SCHEMBL7447087 | 0.92 | CHEK1 (0.34) | CHEK1NSD2 | |
| SCHEMBL7447103 | 0.92 | CHEK1 (0.34) | CHEK1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064648-A1 | ISOQUINOLINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-07 | — | — | WO | disclosed |