Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 7/20 | 0.36 |
| ▸ | NSD2 | O96028 | 6/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403386 | 1.00 | EHMT2 (0.36) | EHMT2NSD2BCHEACHECHEK1 | |
| SCHEMBL7403389 | 1.00 | EHMT2 (0.36) | EHMT2NSD2BCHEACHECHEK1 | |
| SCHEMBL7444417 | 0.99 | EHMT2 (0.35) | EHMT2NSD2BCHEACHECHEK1 | |
| SCHEMBL7393752 | 0.99 | EHMT2 (0.35) | EHMT2NSD2BCHEACHECHEK1 | |
| SCHEMBL7393757 | 0.99 | EHMT2 (0.35) | EHMT2NSD2BCHEACHECHEK1 | |
| SCHEMBL7447087 | 0.94 | CHEK1 (0.34) | EHMT2NSD2CHEK1HTR1A | |
| SCHEMBL7447103 | 0.94 | CHEK1 (0.34) | EHMT2NSD2CHEK1HTR1A | |
| SCHEMBL7447093 | 0.94 | CHEK1 (0.34) | EHMT2NSD2CHEK1HTR1A | |
| SCHEMBL7400404 | 0.93 | CHEK1 (0.37) | NSD2BCHEACHECHEK1LMNA | |
| SCHEMBL7400407 | 0.93 | CHEK1 (0.37) | NSD2BCHEACHECHEK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064648-A1 | ISOQUINOLINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-07 | — | — | WO | claimed |
| WO-2001064648-A1 | ISOQUINOLINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-07 | — | — | WO | disclosed |