Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151578 | 1.00 | CES2 (0.44) | CES2CES1MEN1KMT2AAAK1 | |
| SCHEMBL28584476 | 0.88 | PPARG (0.45) | MEN1KMT2AAAK1NPC1MMP8 | |
| SCHEMBL5149030 | 0.86 | ACHE (0.42) | MEN1KMT2AAAK1NPC1MMP8 | |
| SCHEMBL5310601 | 0.85 | AAK1 (0.46) | MEN1KMT2AAAK1NPC1MMP8 | |
| SCHEMBL27559407 | 0.85 | MEN1 (0.43) | MEN1KMT2AAAK1NPC1MMP8 | |
| SCHEMBL5155521 | 0.84 | RORC (0.40) | MEN1KMT2AAAK1NPC1MMP8 | |
| SCHEMBL7222441 | 0.84 | PPARG (0.43) | MEN1KMT2AAAK1NPC1MMP8 | |
| SCHEMBL5311248 | 0.84 | AAK1 (0.42) | CES2CES1MEN1KMT2AAAK1 | |
| SCHEMBL5155457 | 0.83 | ACHE (0.43) | MEN1KMT2AAAK1NPC1MMP8 | |
| SCHEMBL18554062 | 0.83 | AAK1 (0.40) | MEN1KMT2AAAK1NPC1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |