Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.70 |
| ▸ | CTSB | P07858 | 2/20 | 0.70 |
| ▸ | CTSS | P25774 | 2/20 | 0.70 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 3/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701622 | 0.83 | CTSL (1.00) | CTSLCTSBCTSSCTSK | |
| SCHEMBL2182959 | 0.77 | ANPEP (0.59) | CTSLCTSBCTSSFPR2MMP1 | |
| SCHEMBL4703635 | 0.74 | CTSL (0.41) | CTSLCTSBCTSSFPR2ALDH1A1 | |
| SCHEMBL4703633 | 0.74 | CTSL (0.41) | CTSLCTSBCTSSFPR2ALDH1A1 | |
| SCHEMBL4699978 | 0.72 | GRN (0.47) | CTSLCTSBCTSSFPR2ALDH1A1 | |
| SCHEMBL4699981 | 0.72 | GRN (0.47) | CTSLCTSBCTSSFPR2ALDH1A1 | |
| SCHEMBL4701850 | 0.71 | MAPK8 (0.52) | CTSLCTSBCTSSFPR2ALDH1A1 | |
| SCHEMBL4701848 | 0.71 | MAPK8 (0.52) | CTSLCTSBCTSSFPR2ALDH1A1 | |
| SCHEMBL4698809 | 0.70 | FPR2 (0.68) | FPR2ALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL29516957 | 0.68 | ALDH1A1 (0.59) | FPR2ALDH1A1GRNSORT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002070517-A2 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2002-09-12 | — | — | WO | disclosed |