Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397880 | 0.84 | EPHX1 (0.52) | KMT2ASMN1; SMN2MEN1HDAC1HDAC6 | |
| SCHEMBL7393729 | 0.83 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTPKM | |
| SCHEMBL7399194 | 0.82 | CASR (0.47) | SMN1; SMN2MAPTPKM | |
| SCHEMBL7398740 | 0.79 | SLC6A3 (0.50) | SMN1; SMN2HDAC1HDAC6FOLH1 | |
| SCHEMBL7400931 | 0.78 | SLC6A3 (0.52) | FOLH1 | |
| SCHEMBL7371657 | 0.77 | HDAC1 (0.51) | KMT2APOLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL7400613 | 0.77 | HDAC1 (0.46) | KMT2APOLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL7398715 | 0.75 | MEN1 (0.43) | KMT2ASMN1; SMN2MEN1MAPTHDAC1 | |
| SCHEMBL4212390 | 0.74 | EPHX1 (0.61) | KMT2APOLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL22170203 | 0.71 | POLB (0.67) | KMT2APOLBSMN1; SMN2L3MBTL1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |