Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | FPR2 | P25090 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398740 | 0.89 | SLC6A3 (0.50) | CASRSLC6A3SMN1; SMN2CNR1NPC1 | |
| SCHEMBL7393729 | 0.89 | KMT2A (0.53) | CASRSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL7400931 | 0.88 | SLC6A3 (0.52) | CASRSLC6A3CNR1EPHX1ALDH1A1 | |
| SCHEMBL7397880 | 0.88 | EPHX1 (0.52) | CASRSLC6A3SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL7400611 | 0.82 | KMT2A (0.44) | SMN1; SMN2PKMMAPT | |
| SCHEMBL7398715 | 0.78 | MEN1 (0.43) | SMN1; SMN2RAB9AEPHX1TP53MAPT | |
| SCHEMBL20708118 | 0.78 | SMN1; SMN2 (0.68) | CASRSMN1; SMN2FPR2CNR1NPC1 | |
| SCHEMBL7370963 | 0.76 | L3MBTL1 (0.52) | CASRSMN1; SMN2FPR2CNR1NPC1 | |
| SCHEMBL7399200 | 0.76 | ALDH1A1 (0.47) | CASRSMN1; SMN2FPR2CNR1NPC1 | |
| SCHEMBL15741887 | 0.71 | EPHX1 (0.62) | CASRSMN1; SMN2FPR2CNR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |