Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 8/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398740 | 0.91 | SLC6A3 (0.50) | SLC6A3FOLH1CNR1EPHX1CASR | |
| SCHEMBL7397880 | 0.89 | EPHX1 (0.52) | SLC6A3FOLH1EPHX1CASREPHX2 | |
| SCHEMBL7399194 | 0.88 | CASR (0.47) | SLC6A3CNR1EPHX1CASRALDH1A1 | |
| SCHEMBL7393729 | 0.81 | KMT2A (0.53) | EPHX1CASREPHX2ALDH1A1 | |
| SCHEMBL7398715 | 0.80 | MEN1 (0.43) | EPHX1EPHX2ALDH1A1 | |
| SCHEMBL7400611 | 0.78 | KMT2A (0.44) | FOLH1 | |
| SCHEMBL11048686 | 0.75 | CNR1 (0.70) | SLC6A3CNR1EPHX1CASR | |
| SCHEMBL7368807 | 0.75 | CNR1 (0.56) | SLC6A3FOLH1CNR1EPHX1EPHX2 | |
| SCHEMBL7400935 | 0.75 | CNR1 (0.50) | SLC6A3FOLH1CNR1EPHX1EPHX2 | |
| SCHEMBL11052587 | 0.71 | EPHX1 (0.74) | SLC6A3CNR1EPHX1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |