⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247319 | 0.92 | CA2 (0.33) | — | |
| SCHEMBL7287976 | 0.88 | — | — | |
| SCHEMBL207914 | 0.83 | — | — | |
| SCHEMBL1247046 | 0.80 | — | — | |
| SCHEMBL25403888 | 0.74 | — | — | |
| SCHEMBL1246068 | 0.74 | — | — | |
| SCHEMBL64454 | 0.73 | BLM (0.34) | — | |
| SCHEMBL8745519 | 0.72 | CA2 (0.34) | — | |
| SCHEMBL1035786 | 0.72 | CA2 (0.36) | — | |
| SCHEMBL7400650 | 0.72 | USP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587767-A1 | HYDROXYAZIDO DERIVATIVES AND RELATED COMPOUNDS AS RENIN INHIBITORS | SRI INTERNATIONAL (US) | 1994-03-23 | — | — | EP | disclosed |
| WO-1992021696-A1 | HYDROXYAZIDO DERIVATIVES AND RELATED COMPOUNDS AS RENIN INHIBITORS | SRI INTERNATIONAL (US) | 1992-12-10 | — | — | WO | disclosed |