Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433151 | 0.81 | CTSK (0.47) | CTSK | |
| SCHEMBL14923515 | 0.81 | CTSK (0.47) | CTSK | |
| SCHEMBL19519889 | 0.81 | CTSK (0.47) | CTSK | |
| SCHEMBL7303100 | 0.80 | ALDH1A1 (0.40) | ALDH1A1ASAH1 | |
| SCHEMBL7812736 | 0.79 | MMP2 (0.51) | ALDH1A1 | |
| SCHEMBL27555167 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL6738589 | 0.79 | ELANE (0.47) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL6389343 | 0.79 | ELANE (0.47) | ALDH1A1MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6971175 | 0.77 | ELANE (0.49) | ALDH1A1MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6971183 | 0.77 | ELANE (0.49) | ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047599-A1 | SUCCINAMIDE DERIVATIVES USEFUL AS TNF- AND/OR MMP INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-18 | — | — | WO | disclosed |