Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420638 | 0.85 | NOS2 (0.37) | NOS3NOS2 | |
| SCHEMBL7424315 | 0.84 | NOS3 (0.36) | NOS3NOS2 | |
| SCHEMBL7563046 | 0.83 | NOS2 (0.38) | NOS3NOS2 | |
| SCHEMBL7398095 | 0.82 | KDM4E (0.38) | KMT2ANOS3NOS2 | |
| SCHEMBL7397393 | 0.81 | NOS3 (0.37) | ALDH1A1NOS3NOS2 | |
| SCHEMBL7423582 | 0.79 | NOS2 (0.41) | NOS3NOS2 | |
| SCHEMBL7594951 | 0.78 | NOS3 (0.39) | KMT2ANOS3NOS2 | |
| SCHEMBL7422091 | 0.77 | NOS2 (0.36) | NOS3NOS2 | |
| SCHEMBL7417662 | 0.77 | NOS2 (0.41) | NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7383900 | 0.76 | NOS3 (0.40) | NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000073312-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2000-12-07 | — | — | WO | disclosed |