Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375377 | 0.79 | NOS2 (0.42) | NOS2NOS3 | |
| SCHEMBL7401053 | 0.77 | ALDH1A1 (0.36) | NOS2NOS3 | |
| SCHEMBL7423582 | 0.76 | NOS2 (0.41) | NOS2NOS3 | |
| SCHEMBL7424315 | 0.76 | NOS3 (0.36) | NOS2NOS3 | |
| SCHEMBL7380703 | 0.75 | NOS3 (0.37) | NOS2NOS3 | |
| SCHEMBL7417662 | 0.74 | NOS2 (0.41) | NOS2NOS3 | |
| SCHEMBL7378051 | 0.74 | NOS2 (0.38) | NOS2NOS3 | |
| SCHEMBL7563046 | 0.73 | NOS2 (0.38) | NOS2NOS3 | |
| SCHEMBL7397761 | 0.73 | NOS3 (0.34) | NOS2NOS3 | |
| SCHEMBL7420397 | 0.73 | NOS2 (0.49) | NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000073313-A1 | NEW TRICYCLIC AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2000-12-07 | — | — | WO | disclosed |