Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890358 | 0.88 | ITGB3 (0.57) | SMN1; SMN2HTR7ITGB3ITGA2BMETAP1 | |
| SCHEMBL7398335 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2HTR1AHTR7L3MBTL1ITGB3 | |
| SCHEMBL7403369 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2HTR1AHTR7L3MBTL1ITGB3 | |
| SCHEMBL7397024 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2HTR1AHTR7L3MBTL1ITGB3 | |
| SCHEMBL7334443 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2HTR1AHTR7L3MBTL1DRD2 | |
| SCHEMBL7403379 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2HTR1AHTR7L3MBTL1DRD2 | |
| SCHEMBL9081057 | 0.75 | ITGB3 (0.67) | SMN1; SMN2HTR7ITGB3ITGA2BMETAP1 | |
| SCHEMBL7402988 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2HTR1AHTR7L3MBTL1ITGB3 | |
| SCHEMBL8701303 | 0.73 | ITGB3 (0.41) | SMN1; SMN2ITGB3ITGA2BALDH1A1METAP1 | |
| SCHEMBL7398342 | 0.73 | ITGB3 (0.49) | SMN1; SMN2HTR1AHTR7L3MBTL1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |