Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407497 | 0.89 | SMN1; SMN2 (0.47) | ITGB3ITGA2BSMN1; SMN2HTR1AHTR7 | |
| SCHEMBL9079714 | 0.84 | ITGB3 (0.69) | ITGB3ITGA2BHTR7HRH3GAA | |
| SCHEMBL9275998 | 0.77 | SMN1; SMN2 (0.53) | ITGB3ITGA2BSMN1; SMN2HTR1AHTR7 | |
| SCHEMBL8634940 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BSMN1; SMN2HTR7HRH3 | |
| SCHEMBL8634780 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1HRH3MAPK1HIF1A | |
| SCHEMBL7402988 | 0.76 | SMN1; SMN2 (0.47) | ITGB3ITGA2BSMN1; SMN2HTR1AHTR7 | |
| SCHEMBL7398335 | 0.74 | SMN1; SMN2 (0.53) | ITGB3ITGA2BSMN1; SMN2HTR1AHTR7 | |
| SCHEMBL7401158 | 0.73 | SMN1; SMN2 (0.49) | ITGB3ITGA2BSMN1; SMN2HTR1AHTR7 | |
| SCHEMBL7332630 | 0.72 | ITGB3 (0.59) | ITGB3ITGA2BSMN1; SMN2L3MBTL1HRH3 | |
| SCHEMBL7399702 | 0.69 | SMN1; SMN2 (0.54) | SMN1; SMN2HTR1AHTR7L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |