Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573703 | 0.85 | LTB4R2 (0.44) | NPSR1ALOX15HTTHPGDTAS1R3 | |
| SCHEMBL7879014 | 0.85 | ALDH1A1 (0.38) | NPSR1ALOX15HTTHPGDGAA | |
| SCHEMBL6136371 | 0.83 | MEN1 (0.43) | NPSR1RORCHTTHPGDSMN1; SMN2 | |
| SCHEMBL7869511 | 0.82 | TSHR (0.38) | SMN1; SMN2MAPTALDH1A1POLBMAPK1 | |
| SCHEMBL5897694 | 0.81 | MTNR1A (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL7237747 | 0.77 | GAA (0.37) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL7404622 | 0.76 | TSHR (0.39) | NPSR1HTTHPGDGAASMN1; SMN2 | |
| SCHEMBL7237657 | 0.74 | MEN1 (0.37) | NPSR1HTTHPGDGAASMN1; SMN2 | |
| SCHEMBL6448597 | 0.74 | SLC6A2 (0.40) | CACNA1FCACNA1DCACNA1SCACNA1CNPSR1 | |
| SCHEMBL7404914 | 0.73 | CYP3A4 (0.42) | HTTHPGDTAS1R3TAS1R1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942924-A2 | METHODS AND COMPOUNDS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022494-A2 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | disclosed |