Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869511 | 0.85 | TSHR (0.38) | ALDH1A1LMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7401203 | 0.85 | CACNA1F (0.41) | ALDH1A1HTTSMN1; SMN2ADRB1HPGD | |
| SCHEMBL7237747 | 0.85 | GAA (0.37) | ALDH1A1SMN1; SMN2ADRB2ADRB1ADRB3 | |
| SCHEMBL7574293 | 0.84 | LTB4R2 (0.40) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL5897694 | 0.84 | MTNR1A (0.44) | ALDH1A1 | |
| SCHEMBL6136582 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL7404622 | 0.79 | TSHR (0.39) | ALDH1A1LMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL7401889 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNARAB9AADRB2ADRB1 | |
| SCHEMBL7237657 | 0.77 | MEN1 (0.37) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL6448597 | 0.77 | SLC6A2 (0.40) | ALDH1A1LMNAHTTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333351-B1 | ENZYME INHIBITORS WITH CARRIERS | ATHENA NEUROSCIENCES, INC. | 2001-12-25 | — | — | US | disclosed |
| WO-1998022430-A9 | N-(ARYL/HETEROARYLACETYL) AMINO ACID ESTERS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING b-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | — | 1998-08-20 | — | — | WO | disclosed |