Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 13/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821859 | 1.00 | HCRTR1 (0.40) | HCRTR1HCRTR2KMT2AHTR3EHTR3B | |
| SCHEMBL9821867 | 0.89 | RAB9A (0.48) | KMT2A | |
| SCHEMBL7399041 | 0.89 | RAB9A (0.48) | KMT2A | |
| SCHEMBL7395468 | 0.88 | FABP4 (0.36) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL9821920 | 0.85 | NPC1 (0.47) | HTR3A | |
| SCHEMBL7401003 | 0.85 | NPC1 (0.47) | HTR3A | |
| SCHEMBL9363873 | 0.84 | FABP4 (0.37) | HTR3A | |
| SCHEMBL7396015 | 0.84 | FABP4 (0.37) | HTR3A | |
| SCHEMBL9821927 | 0.84 | TDP1 (0.41) | — | |
| SCHEMBL7397762 | 0.84 | TDP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491770-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-01 | — | — | EP | disclosed |
| EP-0419397-A1 | Substituted urea compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1991-03-27 | — | — | EP | disclosed |
| WO-1991003475-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-03-21 | — | — | WO | disclosed |