Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363873 | 1.00 | FABP4 (0.37) | FABP4FABP5POLBCASP3SENP7 | |
| SCHEMBL7395468 | 0.96 | FABP4 (0.36) | FABP4FABP5POLBCASP3SENP7 | |
| SCHEMBL7401003 | 0.88 | NPC1 (0.47) | POLBCASP3SENP7SENP6HTR3A | |
| SCHEMBL9821920 | 0.88 | NPC1 (0.47) | POLBCASP3SENP7SENP6HTR3A | |
| SCHEMBL7395839 | 0.87 | NPC1 (0.37) | FABP4FABP5HTR3A | |
| SCHEMBL7401919 | 0.87 | FABP4 (0.38) | FABP4FABP5HTR3AKCNH2USP7 | |
| SCHEMBL9359531 | 0.85 | ALDH1A1 (0.39) | FABP4FABP5POLBCA1CA2 | |
| SCHEMBL9359539 | 0.85 | ALDH1A1 (0.39) | FABP4FABP5POLBCA1CA2 | |
| SCHEMBL9821859 | 0.84 | HCRTR1 (0.40) | HTR3A | |
| SCHEMBL7401290 | 0.84 | HCRTR1 (0.40) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491770-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-01 | — | — | EP | claimed |
| WO-1991003475-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-03-21 | — | — | WO | claimed |
| EP-0419397-B1 | Substituted urea compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-06-08 | — | — | EP | disclosed |