Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438340 | 0.89 | LMNA (0.61) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7348701 | 0.85 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7348707 | 0.85 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL15251811 | 0.84 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7064240 | 0.84 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL6793418 | 0.84 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL5840519 | 0.84 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL27575200 | 0.84 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL8684370 | 0.84 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6499290 | 0.83 | SLC1A3 (0.62) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765340-B1 | METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS | CORVAS INT INC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5776927-A | THROMBIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5770600-A | Methionine sulfone and S-substituted cysteine sulfone derivatives as enzyme inhibitors | CORVAS INTERNATIONAL, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| US-5681844-A | ANTITHROMBOTIC AGENTS, ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| US-5658939-A | PREVENTION THROMBOSIS IN MAMMALS | CORVAS INTERNATIONAL INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5646165-A | ANTITHROMBOTIC AGENTS | CORVAS INTERNATIONAL, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0765340-A1 | METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995028420-A1 | METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-10-26 | — | — | WO | disclosed |