Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 5/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATP6V1B1 | P15313 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29113245 | 0.87 | KDM4E (0.51) | KDM4EMAPTHPGDDAOSRD5A2 | |
| SCHEMBL827599 | 0.83 | KDM4E (0.53) | KDM4EMAPTHPGDDAOSRD5A2 | |
| SCHEMBL29614783 | 0.83 | KDM4E (0.53) | KDM4EMAPTHPGDDAOSRD5A2 | |
| Hydrochloric Acid SCHEMBL7218573 | 0.82 | KDM4E (0.51) | KDM4EMAPTHPGDDAOSRD5A2 | |
| 2-Methylindole SCHEMBL9817990 | 0.80 | KDM4E (0.50) | KDM4EMAPTHPGDDAOSRD5A2 | |
| SCHEMBL29156071 | 0.77 | MTNR1A (0.45) | KDM4EMAPTHPGDDAOSRD5A2 | |
| Indole-2-Carboxylic Acid SCHEMBL29781124 | 0.76 | KDM4E (0.80) | KDM4EMAPTHPGDDAOSRD5A2 | |
| SCHEMBL6586200 | 0.74 | KDM4E (0.50) | KDM4EMAPTHPGDDAOSRD5A2 | |
| Trifluoroacetic Acid SCHEMBL31065646 | 0.74 | CYP2A6 (0.72) | KDM4EMAPTHPGDDAOSRD5A2 | |
| Trifluoroacetic Acid SCHEMBL3638793 | 0.74 | KDM4E (0.60) | KDM4EMAPTHPGDDAOSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |