Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21122117 | 0.89 | MEN1 (0.39) | MEN1KMT2AGAAKISS1RTDP1 | |
| SCHEMBL9242626 | 0.83 | GPR84 (0.42) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL27272394 | 0.82 | KISS1R (0.46) | MEN1KMT2AGAAKISS1RTDP1 | |
| SCHEMBL12234274 | 0.81 | MEN1 (0.42) | MEN1KMT2AGAAKISS1RTDP1 | |
| SCHEMBL4741502 | 0.79 | TDP1 (0.42) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL4741507 | 0.79 | TDP1 (0.42) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL5949606 | 0.79 | CA2 (0.46) | CA1CA2CTSKCTSS | |
| SCHEMBL19611472 | 0.78 | MEN1 (0.59) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL19611471 | 0.78 | MEN1 (0.59) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL23151999 | 0.78 | TDP1 (0.44) | MEN1KMT2AGAATDP1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996005185-A1 | NOVEL ALKYLAMINO DERIVATIVES AS SIGMA 2 SELECTIVE LIGANDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-02-22 | — | — | WO | disclosed |