Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13489892 | 0.84 | ALDH1A1 (0.48) | HTR6APPTSHRTAAR1CHRM2 | |
| SCHEMBL7049636 | 0.83 | APP (0.45) | HTR6APPTSHRGAAMAPT | |
| SCHEMBL8221872 | 0.82 | GRIN2D (0.51) | HTR6APPTSHRTAAR1CHRM2 | |
| SCHEMBL18905641 | 0.81 | TSHR (0.48) | HTR6APPTSHRTAAR1GRIN2D | |
| SCHEMBL24521975 | 0.80 | CYP4F2 (0.50) | HTR6APPTSHRTAAR1GRIN2D | |
| SCHEMBL15511268 | 0.80 | TAAR1 (0.57) | HTR6TAAR1 | |
| SCHEMBL27801624 | 0.80 | TDP1 (0.46) | HTR6APPTSHRTAAR1CHRM2 | |
| SCHEMBL30046030 | 0.80 | TAAR1 (0.43) | HTR6APPTSHRTAAR1CHRM2 | |
| SCHEMBL18982883 | 0.78 | LPL (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12017476 | 0.78 | FFAR1 (0.58) | GAAMAPTFFAR1SIRT1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072567-A2 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2002-09-19 | — | — | WO | disclosed |