Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186512 | 0.89 | CYP4A11 (0.47) | CYP4F2CYP4A11SIRT1HTR6GRIN2D | |
| SCHEMBL3150743 | 0.83 | PDK1 (0.49) | ALDH1A1MAPTTSHRAPP | |
| SCHEMBL8221872 | 0.82 | GRIN2D (0.51) | GAAHTR6GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL15823626 | 0.81 | FFAR1 (0.45) | CYP4F2CYP4A11ALDH1A1APP | |
| SCHEMBL8283676 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11SIRT1TDP1TRPV1 | |
| SCHEMBL18905641 | 0.81 | TSHR (0.48) | KDM4EMAPTHTR6GRIN2DGRIN3B | |
| SCHEMBL13489892 | 0.80 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTHTR6GRIN2D | |
| SCHEMBL6096809 | 0.80 | SIRT1 (0.53) | CYP4F2CYP4A11SIRT1TDP1TRPV1 | |
| SCHEMBL7401522 | 0.80 | HTR6 (0.43) | SIRT1GAAMAPTHTR6GRIN2D | |
| SCHEMBL30046030 | 0.80 | TAAR1 (0.43) | HTR6GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015508-A1 | METHODS FOR PREPARING SUBSTITUTED 5,6-DIHYDRO-6-PHENYLBENZO[F]ISOQUINOLIN-2-AMINE | ArQule, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |