Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7965036 | 0.98 | PARP1 (0.44) | PARP1ALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL6235537 | 0.85 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL3110526 | 0.85 | PRKCI (0.49) | PARP1ALDH1A1SMN1; SMN2LMNAATM | |
| Hydrochloric Acid SCHEMBL28054067 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAATMMAPT | |
| SCHEMBL3272963 | 0.81 | MAPT (0.50) | ALDH1A1SMN1; SMN2LMNAATMMAPT | |
| Hydrochloric Acid SCHEMBL19306177 | 0.80 | MAPT (0.49) | ALDH1A1SMN1; SMN2LMNAATMMAPT | |
| SCHEMBL29503140 | 0.77 | PRSS1 (0.61) | PARP1ALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL1002832 | 0.77 | PRSS1 (0.61) | PARP1ALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL9541786 | 0.75 | PARP1 (0.52) | PARP1ALDH1A1SMN1; SMN2LCKKDM4E | |
| SCHEMBL2128609 | 0.75 | PARP1 (0.52) | PARP1ALDH1A1SMN1; SMN2LCKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097921-A1 | Phenylhydrazines | SANOFI-SYNTHELABO (FR) | 2001-05-09 | — | — | EP | disclosed |
| EP-0820444-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996032382-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1996-10-17 | — | — | WO | disclosed |