Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.56 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401121 | 0.87 | ITGB3 (0.57) | ITGB3ITGA2BITGAVACHEKDM1A | |
| SCHEMBL7401634 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BITGAVBRD4ACHE | |
| SCHEMBL7401638 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2BITGAVKDM1AMAOA | |
| SCHEMBL8896406 | 0.74 | — | — | |
| SCHEMBL7396971 | 0.72 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7401120 | 0.72 | ITGB3 (0.58) | ITGB3ITGA2BITGAVKDM1AMAOA | |
| SCHEMBL7433061 | 0.72 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL7401125 | 0.71 | ITGB3 (0.51) | ITGB3ITGA2BFLT1KDRFLT3 | |
| SCHEMBL7400574 | 0.70 | ITGB3 (0.46) | ITGB3ITGA2BITGAVKDM1AMAOA | |
| SCHEMBL7396984 | 0.70 | ITGB3 (0.75) | ITGB3ITGA2BITGAVACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |