Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 6/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 6/20 | 0.37 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400582 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BITGAVKDM1ARCOR1 | |
| SCHEMBL7400579 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BITGAVKDM1ARCOR1 | |
| SCHEMBL7400576 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BITGAVOPRM1OPRD1 | |
| SCHEMBL7400816 | 0.80 | ITGB3 (0.51) | ITGB3ITGA2BITGAVKDM1ARCOR1 | |
| SCHEMBL7433061 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL7396910 | 0.76 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL7396292 | 0.73 | ALDH1A1 (0.39) | ITGB3ITGA2BITGAVMAOAMAOB | |
| SCHEMBL7396296 | 0.73 | ALDH1A1 (0.39) | ITGB3ITGA2BITGAVMAOAMAOB | |
| SCHEMBL7396300 | 0.73 | ALDH1A1 (0.39) | ITGB3ITGA2BITGAVMAOAMAOB | |
| SCHEMBL7401121 | 0.70 | ITGB3 (0.57) | ITGB3ITGA2BITGAVKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |