Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.51 |
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ASF1A | Q9Y294 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401638 | 0.88 | ITGB3 (0.50) | ITGB3ITGA2BMIFMAPTMEN1 | |
| SCHEMBL7401120 | 0.85 | ITGB3 (0.58) | ITGB3ITGA2BFLT1KDRFLT3 | |
| SCHEMBL7401121 | 0.83 | ITGB3 (0.57) | ITGB3ITGA2BMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7401123 | 0.80 | MIF (0.46) | ITGB3ITGA2BMIFMAPTMEN1 | |
| SCHEMBL7402333 | 0.76 | ITGB3 (0.74) | ITGB3ITGA2B | |
| SCHEMBL7433070 | 0.75 | ITGB3 (0.68) | ITGB3ITGA2BMIF | |
| SCHEMBL7401634 | 0.73 | ITGB3 (0.56) | ITGB3ITGA2BFLT1KDRFLT3 | |
| SCHEMBL7400579 | 0.71 | ITGB3 (0.43) | ITGB3ITGA2BMIFMAPTMEN1 | |
| SCHEMBL7401636 | 0.71 | ITGB3 (0.56) | ITGB3ITGA2BFLT1KDRFLT3 | |
| SCHEMBL7400582 | 0.71 | ITGB3 (0.43) | ITGB3ITGA2BMIFMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |