Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903501 | 0.82 | GAA (0.45) | PLA2G2APLA2G5TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL4372563 | 0.81 | CTSK (0.42) | TSHRGAA | |
| Hydrochloric Acid SCHEMBL29798612 | 0.81 | GAA (0.43) | PLA2G2APLA2G5TSHRSMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL28584781 | 0.81 | GAA (0.43) | PLA2G2APLA2G5TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL16894118 | 0.81 | CTSK (0.42) | TSHRGAA | |
| SCHEMBL3958728 | 0.81 | CTSK (0.42) | TSHRGAA | |
| SCHEMBL16041452 | 0.80 | ALDH1A1 (0.40) | PLA2G2APLA2G5TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL16041451 | 0.80 | ALDH1A1 (0.40) | PLA2G2APLA2G5TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL20813495 | 0.80 | TSHR (0.44) | PLA2G2APLA2G5TSHRSMN1; SMN2CA12 | |
| SCHEMBL597202 | 0.78 | SMN1; SMN2 (0.38) | PLA2G2APLA2G5TSHRSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |