Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16041452 | 0.84 | ALDH1A1 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL16041451 | 0.84 | ALDH1A1 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL758494 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL758495 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL597622 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPK1MME | |
| SCHEMBL5074809 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL5074810 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL7401675 | 0.78 | PLA2G2A (0.39) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL4622349 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 | |
| SCHEMBL2551055 | 0.78 | NPSR1 (0.44) | SMN1; SMN2PLA2G2APLA2G5ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180338936-A1 | Methods and Compositions for the Treatment and Prevention of Allergic Rhinitis | MARTIN ALAIN (US) | 2018-11-29 | — | — | US | claimed |
| US-9675569-B2 | Method for treating a pulmonary disease state in mammals by up regulating indigenous in vivo levels of inflammatory agents in mammalian cells | CELLULAR SCIENCES, INC. | 2017-06-13 | — | — | US | claimed |
| US-20160022616-A1 | Method for Treating a Pulmonary Disease State in Mammals by Up Regulating Indigenous in vivo Levels of Inflammatory Agents in Mammalian Cells | CELLULAR SCIENCES, INC. | 2016-01-28 | — | — | US | claimed |
| WO-2013187891-A1 | METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS | MARTIN ALAIN (US) | 2013-12-19 | — | — | WO | claimed |
| US-8211943-B2 | Method for treating a pulmonary disease state in mammals by up regulating indigenous in vivo levels of inflammatory agents in mammalian cells | CELLULAR SCIENCES, INC. | 2012-07-03 | — | — | US | claimed |
| US-8114907-B2 | Method for treating a pulmonary disease state in mammals by up regulating indigenous in vivo levels of inflammatory agents in mammalian cells | CELLULAR SCIENCES INC (US) | 2012-02-14 | — | — | US | claimed |
| EP-1183022-B1 | METHOD AND COMPOSITION FOR TREATING MAMMALIAN NASAL AND SINUS DISEASES CAUSED BY INFLAMMATORY RESPONSE | CELLULAR SCIENCES INC (US) | 2010-12-29 | — | — | EP | claimed |
| EP-2187738-A1 | METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP OR DOWN REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS | Cellular Sciences, Inc. (US) | 2010-05-26 | — | — | EP | claimed |
| US-20090041738-A1 | Method for treating a pulmonary disease state in mammals by up or down regulating indigenous in vivo levels of inflammatory agents in mammalian cells | CELLULAR SCIENCES, INC. | 2009-02-12 | — | — | US | claimed |
| US-20090041739-A1 | Method for treating a pulmonary disease state in mammals by up or down regulating indigenous in vivo levels of inflammatory agents in mammalian cells | CELLULAR SCIENCES, INC. | 2009-02-12 | — | — | US | claimed |
| WO-1998004254-A1 | COMPOSITION OF PYRUVATE AND PROTEIN AND METHOD FOR INCREASING PROTEIN CONCENTRATION IN A MAMMAL | BEALE PAXTON K (US) | 1998-02-05 | — | — | WO | claimed |
| WO-1998004253-A1 | COMPOSITION OF PYRUVATE AND ANTI-CORTISOL COMPOUNDS AND METHOD FOR INCREASING PROTEIN CONCENTRATION IN A MAMMAL | BEALE PAXTON K (US) | 1998-02-05 | — | — | WO | claimed |
| EP-0804181-A1 | METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES CAUSED BY INFLAMMATORY RESPONSE | Cellular Sciences, Inc. (US) | 1997-11-05 | — | — | EP | claimed |
| WO-1997010818-A1 | METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES CAUSED BY INFLAMMATORY RESPONSE | CELLULAR SCIENCES, INC. (US) | 1997-03-27 | — | — | WO | claimed |
| US-5472980-A | Reducing insulin resistance in mammals with amino acid derivatives | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | claimed |
| EP-0636117-A4 | METHOD OF ADMINISTERING PYRUVATE AND METHODS OF SYNTHESIZING PYRUVATE PRECURSORS. | ABBOTT LAB (US) | 1995-07-26 | — | — | EP | claimed |
| EP-0636117-A1 | USE OF PYRUVAMIDE AND SELECTED PYRUVYL-AMINO ACIDS | ABBOTT LABORATORIES (US) | 1995-02-01 | — | — | EP | claimed |
| US-5283260-A | Oral ingesting a pyruvyl-amino acid compound before a glucose tolerance test | ABBOTT LABORATORIES (US) | 1994-02-01 | — | — | US | claimed |
| WO-1993021147-A1 | METHOD OF ADMINISTERING PYRUVATE AND METHODS OF SYNTHESIZING PYRUVATE PRECURSORS | ABBOTT LABORATORIES (US) | 1993-10-28 | — | — | WO | claimed |
| US-5256697-A | Covalently linked pyruvyl-amino compound | ABBOTT LABORATORIES | 1993-10-26 | — | — | US | claimed |