Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KDM5C | P41229 | 2/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861129 | 0.77 | POLB (0.47) | LMNAHTTEGLN1KDM4ENAALAD2 | |
| Trifluoroacetic Acid SCHEMBL8653957 | 0.75 | ALDH1A1 (0.39) | LMNAHTTL3MBTL1EGLN1ECE1 | |
| SCHEMBL5596142 | 0.75 | ADRA1A (0.45) | LMNAEGLN1KDM4EKDM5CPHF8 | |
| SCHEMBL6635766 | 0.74 | HDAC3 (0.50) | LMNAHTTL3MBTL1HDAC3HDAC1 | |
| SCHEMBL12581071 | 0.74 | MEN1 (0.42) | KMT2A | |
| Water SCHEMBL7773341 | 0.73 | ADRA1A (0.43) | LMNAEGLN1KDM4EKDM5CPHF8 | |
| Hydrochloric Acid SCHEMBL8654453 | 0.73 | ADRA1A (0.43) | LMNAEGLN1KDM4EKDM5CPHF8 | |
| SCHEMBL16360052 | 0.72 | LMNA (0.53) | LMNAEGLN1KDM4EKDM5CPHF8 | |
| SCHEMBL3534568 | 0.72 | LMNA (0.41) | LMNAHTTL3MBTL1KDM4EHDAC3 | |
| SCHEMBL6636353 | 0.71 | HDAC1 (0.53) | HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255748-A1 | BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001060813-A1 | BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |