Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450165 | 0.86 | HRH4 (0.50) | HTR2BHPGDF10F9F2 | |
| SCHEMBL7404618 | 0.84 | HPGD (0.43) | HTR2BHPGDF10F9F2 | |
| SCHEMBL7406501 | 0.81 | F2 (0.53) | KMT2AF10F9F2F7 | |
| SCHEMBL7404651 | 0.79 | MAPK14 (0.48) | NPC1KMT2AHPGDF10F2 | |
| SCHEMBL7403653 | 0.79 | F2 (0.49) | F10F9F2F7 | |
| SCHEMBL7410068 | 0.79 | F2 (0.49) | KMT2AF10F9F2F7 | |
| SCHEMBL7404382 | 0.78 | F2 (0.48) | RAB9AKMT2AF10F9F2 | |
| SCHEMBL7408023 | 0.78 | LMNA (0.44) | HTR2BHPGDF10F9ITGB3 | |
| SCHEMBL7406090 | 0.76 | F10 (0.47) | NPC1RAB9AHPGDF10F9 | |
| SCHEMBL2881213 | 0.75 | HPGD (0.71) | NPC1RAB9AHTR2BKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |