Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.60 |
| ▸ | CTSL | P07711 | 7/20 | 0.57 |
| ▸ | CTSB | P07858 | 6/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356041 | 0.82 | CTSL (0.59) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7408631 | 0.79 | CTSS (0.61) | CTSSCTSLCTSBPOLB | |
| SCHEMBL7404835 | 0.79 | CTSS (0.61) | CTSSCTSLCTSBPOLB | |
| SCHEMBL7354956 | 0.77 | CTSS (0.61) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7354953 | 0.77 | CTSS (0.61) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7411947 | 0.77 | CTSS (0.58) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL25004070 | 0.77 | CTSS (0.61) | CTSSCTSLCTSBPOLB | |
| SCHEMBL7275964 | 0.76 | POLB (0.74) | CTSSCTSLCTSBPOLB | |
| SCHEMBL5193787 | 0.76 | POLB (0.74) | CTSSCTSLCTSBPOLB | |
| SCHEMBL7354034 | 0.76 | CTSL (0.83) | CTSSCTSLCTSBCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756625-A4 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARM CORP (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0756625-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995023222-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | KHEPRI PHARMACEUTICALS, INC. (US) | 1995-08-31 | — | — | WO | disclosed |