Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.45 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 13/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406920 | 0.88 | ITGB3 (0.52) | ITGB3ITGAVITGB5ITGB6SMPD1 | |
| SCHEMBL7403157 | 0.81 | SMPD1 (0.43) | SMPD1POLB | |
| SCHEMBL7401084 | 0.80 | SMPD1 (0.50) | SMPD1POLB | |
| SCHEMBL7401023 | 0.79 | SMPD1 (0.45) | SMPD1POLB | |
| SCHEMBL7401929 | 0.78 | ITGB3 (0.47) | ITGB3ITGAVITGB5ITGB6SMPD1 | |
| SCHEMBL7399998 | 0.76 | ITGB3 (0.51) | ITGB3ITGAVITGB5ITGB6 | |
| SCHEMBL13059981 | 0.74 | ITGB3 (0.54) | ITGB3ITGAVITGB5ITGB6 | |
| SCHEMBL6111422 | 0.74 | ITGB3 (0.60) | ITGB3ITGAVITGB5ITGB6 | |
| SCHEMBL5027067 | 0.74 | ITGB3 (0.60) | ITGB3ITGAVITGB5ITGB6 | |
| SCHEMBL7346806 | 0.73 | ITGB3 (0.61) | ITGB3ITGAVITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037492-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |