Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CPN1 | P15169 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7404704 | 0.99 | ALOX15 (0.44) | ITGB3ITGA2BALOX15CPN1CPB2 | |
| SCHEMBL7404093 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7395044 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BST14 | |
| SCHEMBL7273726 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL8543333 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BST14 | |
| SCHEMBL8538055 | 0.81 | ITGB3 (0.54) | ITGB3ITGA2BF2 | |
| Hydrochloric Acid SCHEMBL8573462 | 0.80 | ITGB3 (0.37) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL17907306 | 0.79 | FPR2 (0.39) | — | |
| SCHEMBL8544627 | 0.79 | ITGB3 (0.56) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7400268 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BF2TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0825994-A1 | AMIDINE DERIVATIVES USEFUL AS ANTI-PLATELET AGGREGATION INHIBITORS AND VASODILATORS | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036639-A1 | AMIDINE DERIVATIVES USEFUL AS ANTI-PLATELET AGGREGATION INHIBITORS AND VASODILATORS | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |