Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 14/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405239 | 0.90 | ITGB1 (0.50) | ITGB1ITGA4ITGB7PSMB5PSMB2 | |
| SCHEMBL7406177 | 0.90 | ITGB1 (0.48) | ITGB1ITGA4ITGB7PSMB5PSMB2 | |
| SCHEMBL7407620 | 0.86 | ITGB1 (0.45) | ITGB1ITGA4ITGB7PSMB5PSMB2 | |
| SCHEMBL7202935 | 0.85 | MMP1 (0.53) | ITGB1ITGA4ITGB7MMP1MMP8 | |
| SCHEMBL7406798 | 0.83 | ITGB1 (0.43) | ITGB1ITGA4ITGB7PSMB5PSMB2 | |
| SCHEMBL7405493 | 0.83 | ITGB1 (0.47) | ITGB1ITGA4ITGB7PSMB5PSMB2 | |
| SCHEMBL7406067 | 0.83 | ITGB1 (0.61) | ITGB1ITGA4ITGB7MMP8 | |
| SCHEMBL7408114 | 0.83 | ITGB1 (0.47) | ITGB1ITGA4ITGB7PSMB5PSMB2 | |
| SCHEMBL7763984 | 0.83 | MMP1 (0.55) | ITGB1ITGA4ITGB7MMP1 | |
| SCHEMBL7765671 | 0.83 | MMP1 (0.56) | ITGB1ITGA4ITGB7MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763029-A1 | EPOXYSUCCINIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032954-A1 | EPOXYSUCCINIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-07 | — | — | WO | disclosed |