Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406798 | 0.93 | ITGB1 (0.43) | ITGB1ITGA4ITGB7MMP1PSMB8 | |
| SCHEMBL7406177 | 0.92 | ITGB1 (0.48) | ITGB1ITGA4ITGB7MMP1PSMB8 | |
| SCHEMBL7408114 | 0.91 | ITGB1 (0.47) | ITGB1ITGA4ITGB7MMP1PSMB8 | |
| SCHEMBL7403184 | 0.90 | ITGB1 (0.49) | ITGB1ITGA4ITGB7MMP1PSMB8 | |
| SCHEMBL7408941 | 0.90 | MMP1 (0.45) | ITGB1ITGA4ITGB7MMP1PSMB8 | |
| SCHEMBL7404418 | 0.88 | ITGB1 (0.40) | ITGB1ITGA4ITGB7MMP1PSMB8 | |
| SCHEMBL7407620 | 0.88 | ITGB1 (0.45) | ITGB1ITGA4ITGB7MMP1PSMB8 | |
| SCHEMBL7202935 | 0.86 | MMP1 (0.53) | ITGB1ITGA4ITGB7MMP1MMP8 | |
| SCHEMBL7405493 | 0.85 | ITGB1 (0.47) | ITGB1ITGA4ITGB7MMP1PSMB8 | |
| SCHEMBL7406067 | 0.85 | ITGB1 (0.61) | ITGB1ITGA4ITGB7MMP8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763029-A1 | EPOXYSUCCINIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032954-A1 | EPOXYSUCCINIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-07 | — | — | WO | disclosed |